Massachusetts, that attracted thousands of tourists from across the United States. Beginning July 10, the Massachusetts Department of Public Health (MA DPH) received reports of an increase in COVID-19 cases among persons who reside in or recently visited Barnstable County, including in fully vaccinated persons. Persons with COVID-19 reported attending densely packed indoor and outdoor events at venues that included bars, restaurants, guest houses, and rental homes. On July 3, MA DPH had reported a 14-day average COVID-19 incidence of zero cases per 100,000 persons per day in residents of the town in Barnstable County; by July 17, the 14-day average incidence increased to 177 cases per 100,000 persons per day in residents of the town (2). During July 10–26, using travel history data from the state COVID-19 surveillance system, MA DPH identified a cluster of cases among Massachusetts residents. Additional cases were identified by local health jurisdictions through case investigation. COVID-19 cases were matched with the state immunization registry. A cluster-associated case was defined as receipt of a positive SARS-CoV-2 test (nucleic acid amplification or antigen) result ≤14 days after travel to or residence in the town in Barnstable County since July 3. COVID-19 vaccine breakthrough cases were those in fully vaccinated Massachusetts residents (those with documentation from the state immunization registry of completion of COVID-19 vaccination as recommended by the Advisory Committee on Immunization Practices,† ≥14 days before exposure). Specimens were submitted for whole genome sequencing§ to either the Massachusetts State Public Health Laboratory or the Broad Institute of the Massachusetts Institute of

Massachusetts, yang menarik ribuan turis dari seluruh Amerika Serikat. Mulai 10 Juli, Departemen Kesehatan Masyarakat Massachusetts (MA DPH) menerima laporan tentang peningkatan kasus COVID-19 di antara orang-orang yang tinggal di atau baru-baru ini mengunjungi Barnstable County, termasuk pada orang yang divaksinasi penuh. Orang dengan COVID-19 dilaporkan menghadiri acara indoor dan outdoor yang padat di tempat-tempat yang mencakup bar, restoran, wisma, dan rumah sewaan. Pada 3 Juli, MA DPH telah melaporkan insiden COVID-19 rata-rata 14 hari dari nol kasus per 100.000 orang per hari di penduduk kota di Barnstable County; pada 17 Juli, insiden rata-rata 14 hari meningkat menjadi 177 kasus per 100.000 orang per hari di penduduk kota (2). Selama 10-26 Juli, menggunakan data riwayat perjalanan dari sistem pengawasan COVID-19 negara bagian, MA DPH mengidentifikasi sekelompok kasus di antara penduduk Massachusetts. Kasus tambahan diidentifikasi oleh yurisdiksi kesehatan setempat melalui investigasi kasus. Kasus COVID-19 dicocokkan dengan daftar imunisasi negara. Kasus terkait cluster didefinisikan sebagai penerimaan hasil tes SARS-CoV-2 positif (amplifikasi asam nukleat atau antigen) 14 hari setelah perjalanan ke atau tinggal di kota di Barnstable County sejak 3 Juli.Kasus terobosan vaksin COVID-19 adalah mereka yang berada di penduduk Massachusetts yang divaksinasi penuh (mereka yang memiliki dokumentasi dari pendaftaran imunisasi negara bagian tentang penyelesaian vaksinasi COVID-19 seperti yang direkomendasikan oleh Komite Penasihat tentang Praktik Imunisasi, 14 hari sebelum paparan). Spesimen diserahkan untuk pengurutan seluruh genom, baik ke Laboratorium Kesehatan Masyarakat Negara Bagian Massachusetts atau Institut Luas dari Institut Massachusetts.